Sinus tarsi syndrome is a clinical disorder of persistent pain and tenderness localised to the sinus tarsi — a small cone-shaped canal on the outer (lateral) side of the hindfoot, sitting between the talus (ankle bone) and the calcaneus (heel bone) at the level of the subtalar joint.
Within this tunnel lie important ligaments (the cervical and interosseous ligaments), nerves, fat and blood vessels that contribute to proprioception and subtalar joint stability. When these structures become inflamed or scarred — most commonly following an ankle sprain — the resulting irritation produces deep, aching pain and a characteristic feeling of ankle instability.
Sinus tarsi syndrome is frequently confused with a chronic lateral ankle sprain or general ankle pain, and patients often wait months before receiving an accurate diagnosis. With the correct clinical assessment and treatment it typically responds well to conservative management.

